Awesome song from an awesome band !!

Band: Behemoth
Album: The Satanist
Song: O Father O Satan O Sun!
Country: Poland

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Let’s Talk Pasta for a minute! Use Code DLAUER10 on Natural Heaven Low-Carb Pasta: https://eatnaturalheaven.com/products/angel-hair-veggie-noodles-natural-heaven

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Stay Lean Year Round- Olive Oil is Crucial (High Fat Superfood Series)- Thomas DeLauer

Special Thanks to my team and Nicholas Norwitz – Oxford PhD Researcher and Harvard Med Student – for working diligently on research as well!

It’s important that I am honest and to say that this video does have a sponsorship from Natural Heaven, supporting them is a good way to support my channel!

MUFA, Oleic Acid, OEA

The MUFA, oleic acid, is the main fatty acid in olive oil. The name, “oleic acid” comes from the Latin, “oleum” meaning “oil.” Basically, I’m saying that EVOO is the original gangster (OG) of oils.

Oleoylethanolamine (OEA) synthesis: Dietary oleic acid is converted into OAE through the two-step “transacylation-phosphodiesterase pathway.” First, oleic acid is converted into N-oleoyl-phosphatidylethanolamine (NOPE) by the enzyme NAT, then NOPE is converted into OAE by the enzyme NAPE-PLD. The synthesis of OEA occurs in the small intestine, liver, and within most peripheral tissues. In fact, it’s been suggested that the reason plasma OEA correlates with oleic acid consumption is not because OEA is being produced in the intestines/liver and being transported, but rather than OEA can spill over into the bloodstream after being synthesized from oleic acid by peripheral tissues.

OEA signaling: OEA binds the transcription factor PPARα, which causes PPARα to form a heterodimer with RXR that binds to PPARα response elements on DNA and increases the expression of several genes, including those involved in lipid transport, β-oxidation, lipoprotein uptake, etc. Specifically, PPARα increases the expression of the fat transporter protein CD36 and uncoupling (fat-browning) protein UCP-2 to increase fat burning. OEA also binds the TRPV1 receptor the stimulation of which sends a satiety signal from the gut to the brain via the Vagus nerve. Interestingly, it appears that the cuddle hormone, oxytocin, is important in this mechanism. The Vagus nerve talks to the nucleus of the solitary tract in the hypothalamus, stimulating oxytocin release and inducing satiety.

OEA knockout rats: Rats lacking the enzyme, NAPE-LD, that makes OEA from oleic acid exhibit obesity, insulin resistance, increased cholesterol and triglycerides, increased inflammation, and an impaired fat browning in response to cold.
Progress in Lipid Research 2017, Review https://www.ncbi.nlm.nih.gov/pubmed/28389247

Polyphenols (Oleocanthal & Hydroxytyrosol)
EVOO contains at least 36 different antioxidant polyphenols. It’s impossible to concisely characterize the benefits of all 36, so we will discuss just two examples: oleocanthal and hydroxytyrosol.

Oleocanthal
Inflammation. Oleocanthal inhibits the pro-inflammatory COX enzymes that contribute to a wide manner of inflammatory diseases Nature 2005 https://www.nature.com/articles/437045a

Alzheimer’s: https://www.ncbi.nlm.nih.gov/pubmed/19631677

Alzheimer’s: https://www.ncbi.nlm.nih.gov/pubmed/19549281

Hydroxytyrosol
Hydorxytyrosol is another phenolic compound found at high levels in EVOO. It is among the strongest antioxidants found in nature, with 10-times the antioxidant power of green tea.

Refined olive oils and fake EVOOS contain only about 10% the hydroxytyrosol as found in true EVOO.

Hydroxytyrosol concentrations in olives vary by variety. Greek black olives contain 100-340 mg/kg, whereas Greek kalamata olives contain 250-750 mg/kg.

Heart. The European Food & Safety Authority has stated that hydroxytyrosol protects the cardiovascular system and prevents atherosclerosis.

Brain. Hydroxytyrosol protects against Alzheimer’s and Parkinson’s disease by crossing the blood-brain barrier and protecting the brain’s precious fats from oxidation.

Cancer. Consumption of 50 µM–100 µM hydroxytyrosol, from EVOO or olives, has been shown to inhibit the growth of leukemia, adenocarcinoma, colon cancer, and breast cancer cells.

Medicines 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874578

Nicholas Norwitz – Oxford PhD Researcher and Harvard Med Student:
https://www.dpag.ox.ac.uk/team/nicholas-norwitz

Take in the divine aroma of quality Italian cuisine at the Fat Olive Restaurant! Owner, Dino Dassie has taken his passion of Italian cooking and turned it into a thriving business, opening the doors to Fat Olive with his wife, Carla in 2019. The restaurant takes pride in the traditional style of cooking; offering local, quality and fresh ingredients in staple dishes like basil pesto, chicken parmigiana, fettucine alfredo, and Stromboli.

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The debate over what causes weight gain has raged for years. Is it excess calories that cause weight gain, or do carbs make you fat? All the content I see on this topic seems to gloss over the effects fructose has on our bodies – which is key to understanding why we gain weight.

– THE CARB DODGING CHALLENGE –
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– RESOURCES MENTIONED –

Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial – https://www.bmj.com/content/363/bmj.k4583

The carbohydrate-insulin model: a physiological perspective on the obesity pandemic – https://academic.oup.com/ajcn/article/114/6/1873/6369073

Fructose, insulin resistance, and metabolic dyslipidemia – https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-5

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans – https://www.jci.org/articles/view/37385

Global prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in the overweight and obese population: a systematic review and meta-analysis – https://www.thelancet.com/journals/langas/article/PIIS2468-1253(22)00317-X/fulltext

Public Health Collaboration (PHC) List of Randomised Controlled Trials (RCTS) Comparing Low-Carb Diets Of Less Than 130g Carbohydrate Per Day To Low-Fat Diets Of Less Than 35% Fat Of Total Calories – https://phcuk.org/evidence/rcts/

– IMPORTANT –
The content in this video is not intended as a substitute for the medical advice of a primary physician. Please regularly consult with your physician in matters relating to your health, particularly with respect to any symptoms that may require diagnosis or immediate medical attention. Due to the variance of individuals’ lifestyles and bodies, the methods elaborated on in this video are not guaranteed to produce your desired result; therefore, the author does not assume any liability to any party for any loss, damage, or disruption caused by the choice to implement any of the following health strategies.

ER physician Travis Stork offers the real deal behind the common misconception that eating carbs right before bed can cause you to gain weight.

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The Doctors is an Emmy award-winning daytime talk show hosted by ER physician Dr. Travis Stork, plastic surgeon Dr. Andrew Ordon, OB-GYN Dr. Jennifer Ashton, urologist Dr. Jennifer Berman and family medicine physician and sexologist Dr. Rachael Ross.

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There weren’t many people online today but I did manage to find a game. It is a classic Playstation 3 game indeed. Had a lot of fun when I played this game way back then.

#playstation #fatprincess #ps3
Video Rating: / 5

Review on Fat Princess: An action real-time strategy video game developed by Titan Studios and published by Sony Computer Entertainment for the PlayStation 3. It was released in North America, Europe and Australia on July 30, 2009, and in Japan on December 25, 2009 as Pocchari Princess. This game is heavily underrated and one of my favorite games of all time. Unfortunately Sony revived the game with a sequel with a more cooperative beat- em up twist rather than staying true to the original.

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舊作品
Ultraman SAGA MAD
AKB48 – Lost the way
By_小兴
http://weibo.com/zeroxsx
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(真正的戰鬥現在才開始)

請勿盜片，此影片為Jing Hill製作

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